Dive Into the Lives of OMF Surgeons Around the World

Our study maps the invasive front of oral cancer using spatial transcriptomics. We found that tumor cells are aided by an "accomplice": activated myofibroblastic CAFs (myCAFs). Through ECM-CD44 crosstalk, myCAFs enhance tumor cell stemness, creating a metastatic niche. From this interaction, we extracted a spatially resolved, 23-gene signature that predicts both lymph node metastasis and poor survival, which offers new prognostic biomarkers and therapeutic targets.

By applying AI analysis of biomarkers unique to your patient’s lesion, Straticyte™ provides deeper insight and analysis helping you and your patient make more informed decisions on treatment and surveillance with confidence.